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soluble cd25 (scd25)  (R&D Systems)


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    Structured Review

    R&D Systems soluble cd25 (scd25)
    Treg numbers and suppressive function increased with CTLA4-Ig/IL-2 treatment throughout the 48-week treatment period. Changes in Treg suppressive function (A) , the percentage of CD4 + <t>CD25</t> + FOXP3 + cells (B) , the percentage of CD4 + CD25 + cells (C) , the percentage of CD4 + CD25 − cells (D) , and the percentage of CD8 + cells (E) throughout the study are shown. Changes in CD25 protein expression (F) and FOXP3 protein expression (G) in the CD4 + CD25 + FOXP3 + population by mean fluorescent intensity (MFI) throughout the study are shown. Data were analyzed by a one-way ANOVA with post-hoc Tukey test and p values less than 0.05 were considered significant. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01.
    Soluble Cd25 (Scd25), supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/soluble+cd25+%28scd25%29/pmc11195540-115-3-10?v=R%26D+Systems
    Average 90 stars, based on 1 article reviews
    soluble cd25 (scd25) - by Bioz Stars, 2026-07
    90/100 stars

    Images

    1) Product Images from "A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis"

    Article Title: A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis

    Journal: Frontiers in Neurology

    doi: 10.3389/fneur.2024.1415106

    Treg numbers and suppressive function increased with CTLA4-Ig/IL-2 treatment throughout the 48-week treatment period. Changes in Treg suppressive function (A) , the percentage of CD4 + CD25 + FOXP3 + cells (B) , the percentage of CD4 + CD25 + cells (C) , the percentage of CD4 + CD25 − cells (D) , and the percentage of CD8 + cells (E) throughout the study are shown. Changes in CD25 protein expression (F) and FOXP3 protein expression (G) in the CD4 + CD25 + FOXP3 + population by mean fluorescent intensity (MFI) throughout the study are shown. Data were analyzed by a one-way ANOVA with post-hoc Tukey test and p values less than 0.05 were considered significant. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01.
    Figure Legend Snippet: Treg numbers and suppressive function increased with CTLA4-Ig/IL-2 treatment throughout the 48-week treatment period. Changes in Treg suppressive function (A) , the percentage of CD4 + CD25 + FOXP3 + cells (B) , the percentage of CD4 + CD25 + cells (C) , the percentage of CD4 + CD25 − cells (D) , and the percentage of CD8 + cells (E) throughout the study are shown. Changes in CD25 protein expression (F) and FOXP3 protein expression (G) in the CD4 + CD25 + FOXP3 + population by mean fluorescent intensity (MFI) throughout the study are shown. Data were analyzed by a one-way ANOVA with post-hoc Tukey test and p values less than 0.05 were considered significant. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01.

    Techniques Used: Expressing



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    Treg numbers and suppressive function increased with CTLA4-Ig/IL-2 treatment throughout the 48-week treatment period. Changes in Treg suppressive function (A) , the percentage of CD4 + <t>CD25</t> + FOXP3 + cells (B) , the percentage of CD4 + CD25 + cells (C) , the percentage of CD4 + CD25 − cells (D) , and the percentage of CD8 + cells (E) throughout the study are shown. Changes in CD25 protein expression (F) and FOXP3 protein expression (G) in the CD4 + CD25 + FOXP3 + population by mean fluorescent intensity (MFI) throughout the study are shown. Data were analyzed by a one-way ANOVA with post-hoc Tukey test and p values less than 0.05 were considered significant. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01.
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    Treg numbers and suppressive function increased with CTLA4-Ig/IL-2 treatment throughout the 48-week treatment period. Changes in Treg suppressive function (A) , the percentage of CD4 + <t>CD25</t> + FOXP3 + cells (B) , the percentage of CD4 + CD25 + cells (C) , the percentage of CD4 + CD25 − cells (D) , and the percentage of CD8 + cells (E) throughout the study are shown. Changes in CD25 protein expression (F) and FOXP3 protein expression (G) in the CD4 + CD25 + FOXP3 + population by mean fluorescent intensity (MFI) throughout the study are shown. Data were analyzed by a one-way ANOVA with post-hoc Tukey test and p values less than 0.05 were considered significant. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01.
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    Boehringer Mannheim soluble cd25 (scd25
    Synovial fluid parameters
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    Image Search Results


    Treg numbers and suppressive function increased with CTLA4-Ig/IL-2 treatment throughout the 48-week treatment period. Changes in Treg suppressive function (A) , the percentage of CD4 + CD25 + FOXP3 + cells (B) , the percentage of CD4 + CD25 + cells (C) , the percentage of CD4 + CD25 − cells (D) , and the percentage of CD8 + cells (E) throughout the study are shown. Changes in CD25 protein expression (F) and FOXP3 protein expression (G) in the CD4 + CD25 + FOXP3 + population by mean fluorescent intensity (MFI) throughout the study are shown. Data were analyzed by a one-way ANOVA with post-hoc Tukey test and p values less than 0.05 were considered significant. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01.

    Journal: Frontiers in Neurology

    Article Title: A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis

    doi: 10.3389/fneur.2024.1415106

    Figure Lengend Snippet: Treg numbers and suppressive function increased with CTLA4-Ig/IL-2 treatment throughout the 48-week treatment period. Changes in Treg suppressive function (A) , the percentage of CD4 + CD25 + FOXP3 + cells (B) , the percentage of CD4 + CD25 + cells (C) , the percentage of CD4 + CD25 − cells (D) , and the percentage of CD8 + cells (E) throughout the study are shown. Changes in CD25 protein expression (F) and FOXP3 protein expression (G) in the CD4 + CD25 + FOXP3 + population by mean fluorescent intensity (MFI) throughout the study are shown. Data were analyzed by a one-way ANOVA with post-hoc Tukey test and p values less than 0.05 were considered significant. Data are expressed as mean ± SD. * p < 0.05, ** p < 0.01.

    Article Snippet: Levels of soluble CD25 (sCD25) were also assayed by ELISA (R&D Systems, Cat# DR2A00) using sera from participants ( n = 4) and healthy controls ( n = 23) according to the manufacturer’s instructions.

    Techniques: Expressing

    Synovial fluid parameters

    Journal:

    Article Title: Increased synovial fluid levels of soluble CD23 are associated with an erosive status in rheumatoid arthritis (RA)

    doi: 10.1046/j.1365-2249.2000.01198.x

    Figure Lengend Snippet: Synovial fluid parameters

    Article Snippet: SF levels of sCD23, IL-1β, IL-3, IL-4, IL-6, IL-8, IL-10, IL-12 (Biosource Europe (formerly Medgenix), Fleurus, Belgium) and soluble CD25 (sCD25; Boehringer, Mannheim, Germany) were simultaneously determined by ELISA using specific MoAbs and according to the manufacturer’s recommendations.

    Techniques:

    Positive linear correlation between log soluble CD23 and log soluble CD25 in erosive knee−/hand+ RA (○) and erosive knee+/hand+ RA (•). r and P values are those obtained for the two groups studied together.

    Journal:

    Article Title: Increased synovial fluid levels of soluble CD23 are associated with an erosive status in rheumatoid arthritis (RA)

    doi: 10.1046/j.1365-2249.2000.01198.x

    Figure Lengend Snippet: Positive linear correlation between log soluble CD23 and log soluble CD25 in erosive knee−/hand+ RA (○) and erosive knee+/hand+ RA (•). r and P values are those obtained for the two groups studied together.

    Article Snippet: SF levels of sCD23, IL-1β, IL-3, IL-4, IL-6, IL-8, IL-10, IL-12 (Biosource Europe (formerly Medgenix), Fleurus, Belgium) and soluble CD25 (sCD25; Boehringer, Mannheim, Germany) were simultaneously determined by ELISA using specific MoAbs and according to the manufacturer’s recommendations.

    Techniques:

    Significant correlations for sCD23 and IL-10 in erosive rheumatoid arthritis

    Journal:

    Article Title: Increased synovial fluid levels of soluble CD23 are associated with an erosive status in rheumatoid arthritis (RA)

    doi: 10.1046/j.1365-2249.2000.01198.x

    Figure Lengend Snippet: Significant correlations for sCD23 and IL-10 in erosive rheumatoid arthritis

    Article Snippet: SF levels of sCD23, IL-1β, IL-3, IL-4, IL-6, IL-8, IL-10, IL-12 (Biosource Europe (formerly Medgenix), Fleurus, Belgium) and soluble CD25 (sCD25; Boehringer, Mannheim, Germany) were simultaneously determined by ELISA using specific MoAbs and according to the manufacturer’s recommendations.

    Techniques: